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Hiroaki Okamoto Selected Research

Hepatitis E

5/2021Loss of antibodies to hepatitis E virus in organ transplant patients with hepatitis E.
7/2020Clinical and virologic features of hepatitis E virus infection at a university hospital in Japan between 2000 and 2019.
1/2020IFN-λ3 as a host immune response in acute hepatitis E virus infection.
10/2019Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro.
1/2019Screening of novel drugs for inhibiting hepatitis E virus replication.
1/2018Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review.
11/2017Characterization of the Quasi-Enveloped Hepatitis E Virus Particles Released by the Cellular Exosomal Pathway.
4/2017Autochthonous sporadic acute hepatitis E caused by two distinct subgenotype 3b hepatitis E virus strains with only 90% nucleotide identity.
2/2016Prevalence of hepatitis viruses in patients with acute hepatitis and characterization of the detected genotype 4 hepatitis E virus sequences in Mongolia.
9/2015Recent Trend of Hepatitis E Virus Infection in Chiba Area, Japan: 3 of 5 Cases with Rheumatoid Arthritis.
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Hiroaki Okamoto Research Topics

Disease

65Infections
08/2022 - 09/2002
42Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 09/2009
27Hepatitis E
05/2021 - 02/2003
24Hepatitis
05/2022 - 09/2002
23Neoplasms (Cancer)
01/2022 - 06/2003
14Hepatitis B
05/2022 - 09/2002
11Hepatocellular Carcinoma (Hepatoma)
05/2022 - 08/2002
11Disease Progression
11/2021 - 06/2005
11Lung Neoplasms (Lung Cancer)
11/2021 - 05/2002
11Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2020 - 08/2006
10Neutropenia
01/2020 - 09/2009
10Massive Hepatic Necrosis
01/2018 - 07/2005
9Pneumonia (Pneumonitis)
01/2022 - 01/2007
8Chronic Hepatitis C
05/2022 - 06/2002
8Hepatitis A (Hepatitis, Infectious)
01/2022 - 03/2004
8Chronic Hepatitis (Chronic Active Hepatitis)
04/2020 - 08/2006
8Viremia
07/2009 - 08/2002
7Febrile Neutropenia
01/2020 - 01/2014
6Virus Diseases (Viral Diseases)
05/2022 - 10/2002
6Interstitial Lung Diseases (Interstitial Lung Disease)
01/2022 - 06/2003
6Glioma (Gliomas)
02/2008 - 09/2004
5Idiopathic Pulmonary Fibrosis
01/2021 - 03/2008
5Thrombocytopenia (Thrombopenia)
01/2020 - 07/2012
5Liver Diseases (Liver Disease)
01/2014 - 08/2002
4Fibrosis (Cirrhosis)
07/2021 - 08/2002
3Acute Liver Failure (Fulminant Hepatic Failure)
05/2022 - 02/2017
3Anorexia
01/2020 - 01/2016
3Anemia
01/2020 - 05/2007
3Radiation Pneumonitis
01/2020 - 01/2014
3Diarrhea
01/2020 - 12/2009
3Neoplasm Metastasis (Metastasis)
10/2019 - 11/2006
3Coinfection
04/2017 - 02/2003
3Autoimmune Hepatitis
09/2015 - 06/2005
3Hemangioblastoma
03/2007 - 04/2006
3Glioblastoma (Glioblastoma Multiforme)
05/2005 - 01/2004
2Persistent Infection
05/2022 - 11/2015
2Idiopathic Interstitial Pneumonias
01/2022 - 01/2020
2Hemophilia A (Haemophilia)
12/2021 - 05/2005

Drug/Important Bio-Agent (IBA)

35RNA (Ribonucleic Acid)IBA
01/2022 - 08/2002
26AntibodiesIBA
05/2021 - 09/2002
19Carboplatin (JM8)FDA LinkGeneric
01/2020 - 08/2006
17DNA (Deoxyribonucleic Acid)IBA
08/2021 - 08/2002
16Immunoglobulin G (IgG)IBA
08/2022 - 02/2003
16Proteins (Proteins, Gene)FDA Link
12/2021 - 10/2004
16Immunoglobulin M (IgM)IBA
08/2021 - 09/2002
15Cisplatin (Platino)FDA LinkGeneric
01/2022 - 12/2009
13Hepatitis B Surface Antigens (HBsAg)FDA Link
05/2022 - 09/2002
12Immunoglobulin A (IgA)IBA
07/2020 - 02/2003
11NucleotidesIBA
02/2022 - 04/2006
10Docetaxel (Taxotere)FDA Link
01/2021 - 06/2012
8Antiviral Agents (Antivirals)IBA
02/2022 - 10/2013
8EnzymesIBA
01/2022 - 09/2002
8ErbB Receptors (EGF Receptor)IBA
11/2021 - 05/2011
8Irinotecan (Camptosar)FDA LinkGeneric
01/2017 - 08/2006
7Pharmaceutical PreparationsIBA
01/2022 - 01/2007
7Pemetrexed (MTA)FDA Link
06/2020 - 10/2013
7Etoposide (VP 16)FDA LinkGeneric
01/2020 - 08/2006
6Bevacizumab (Avastin)FDA Link
06/2020 - 06/2012
6Alanine Transaminase (SGPT)IBA
04/2020 - 09/2002
6Transaminases (Aminotransferases)IBA
11/2018 - 01/2008
5Immune Checkpoint InhibitorsIBA
01/2022 - 01/2020
5Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2021 - 09/2015
5VaccinesIBA
01/2021 - 11/2003
5InterferonsIBA
11/2020 - 06/2002
5Ribavirin (Virazole)FDA LinkGeneric
10/2019 - 10/2013
5AntigensIBA
06/2016 - 01/2005
5ProteomeIBA
10/2011 - 10/2004
4glecaprevir and pibrentasvirIBA
05/2022 - 12/2019
4Adrenal Cortex Hormones (Corticosteroids)IBA
11/2021 - 01/2007
4amrubicinIBA
01/2021 - 12/2006
4Biomarkers (Surrogate Marker)IBA
06/2019 - 06/2005
4Immunoglobulin IsotypesIBA
11/2018 - 07/2005
3atezolizumabIBA
01/2022 - 01/2020
3BilirubinIBA
06/2021 - 09/2002
3Tyrosine Kinase InhibitorsIBA
01/2021 - 10/2018
3Paclitaxel (Taxol)FDA LinkGeneric
01/2020 - 09/2009
3Gefitinib (Iressa)FDA Link
10/2018 - 05/2011
3Immunoglobulins (Immunoglobulin)IBA
09/2017 - 11/2012
3Messenger RNA (mRNA)IBA
10/2016 - 01/2004
3ImmunosorbentsIBA
08/2015 - 12/2004
3Prednisolone (Predate)FDA LinkGeneric
01/2015 - 06/2005
3Prothrombin (Factor II)IBA
08/2009 - 07/2005
3Biological ProductsIBA
03/2007 - 10/2005
2Nucleic AcidsIBA
08/2022 - 01/2020
2favipiravirIBA
05/2022 - 02/2022
2Subgenomic RNAIBA
05/2022 - 02/2022
2Hepatitis A AntibodiesIBA
02/2022 - 08/2006
2Circular DNAIBA
02/2022 - 03/2020
2pembrolizumabIBA
12/2021 - 12/2020
2B7-H1 AntigenIBA
12/2021 - 12/2020

Therapy/Procedure

34Drug Therapy (Chemotherapy)
12/2021 - 05/2002
30Therapeutics
05/2022 - 05/2005
11Radiotherapy
01/2022 - 05/2007
10Blood Transfusion (Blood Transfusions)
05/2022 - 08/2002
8Liver Transplantation
05/2022 - 11/2003
8Chemoradiotherapy
01/2022 - 06/2012
4Combination Drug Therapy (Combination Chemotherapy)
07/2019 - 08/2006
3Transplantation
01/2020 - 11/2003
3Adjuvant Chemotherapy
01/2020 - 11/2018
3Renal Dialysis (Hemodialysis)
05/2007 - 12/2004